BIIB021 (mesylate)

Catalog NO.:A903995
CAS NO.:1225041-97-3
MDL NO.:
EINECS NO.:
Synonyms: BIIB 021 mesylate;CNF 2024 mesylate;CNF-2024 mesylate; 6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine methanesulfonate
Quality Control & MSDS
Product Details
CAS NO.:1225041-97-3
Appearance:
Molecular Formula:C15H19ClN6O4S
Formula Weight:414.87
Melting Point:
Boiling Point:
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Density:
Storage Condition:Store in a tightly closed container, in a cool and dry place.
Description

BIIB021, also known as CNF2024, is an orally active, purine-scaffold, small-molecule inhibitor of heat shock protein 90 (HSP90) with potential antineoplastic activity. HSP90 inhibitor CNF2024 specifically blocks active HSP90, inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival; this may result in the inhibition of cellular proliferation in susceptible tumor cell populations.

1225041-97-3 (mesylate)

848695-25-0 (free base)

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