Infigratinib monohydrate

Catalog NO.:A903979
CAS NO.:1310746-11-2
MDL NO.:
EINECS NO.:
Synonyms: 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea
Quality Control & MSDS
Product Details
CAS NO.:1310746-11-2
Appearance:
Molecular Formula:C26H33Cl2N7O4
Formula Weight:578.50
Melting Point:
Boiling Point:
Flash Point:
Density:
Storage Condition:Store in a tightly closed container, in a cool and dry place.
Description

Infigratinib, also known as, BGJ398 or NVP-BGJ398, is a pan FGFR kinase inhibitor, and is an orally bioavailable pan inhibitor of human fibroblast growth factor receptors (FGFRs) with potential antiangiogenic and antineoplastic activities. pan FGFR kinase inhibitor BGJ398 selectively binds to and inhibits the activities of FGFRs, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death.

872511-34-7 (free base)

1310746-10-1 (phosphate)

1310746-11-2 (monohydrate)

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