Talabostat mesylate

Catalog NO.:A903812
CAS NO.:150080-09-4
MDL NO.:
EINECS NO.:
Synonyms: [(2R)-1-[(2S)-2-Amino-3-methylbutanoyl]pyrrolidin-2-yl]boronic acid mesylate
Quality Control & MSDS
Product Details
CAS NO.:150080-09-4
Appearance:Off-white solid
Molecular Formula:C10H23BN2O6S
Formula Weight:310.18
Melting Point:
Boiling Point:
Flash Point:
Density:
Storage Condition:Store in a tightly closed container, in a cool and dry place.
Description

Talabostat, also known as PT-100, is dipeptidyl peptidase inhibitor with antineoplastic and hematopoiesis- stimulating activities. By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat inhibits dipeptidyl peptidases, such as fibroblast activation protein (FAP), resulting in the stimulation of cytokine and chemokine production and specific T-cell immunity and T-cell- dependent activity. This agent may also stimulate the production of colony stimulating factors, such as granulocyte colony stimulating factor (G-CSF), resulting in the stimulation of hematopoiesis. Dipeptidyl peptidases are involved in the activation of polypeptide hormones and chemokines.

150080-09-4 (mesylate)

149682-77-9 (free base)

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