CHIR99021 trihydrochloride

Catalog NO.:A904010
CAS NO.:1782235-14-6
MDL NO.:
EINECS NO.:
Synonyms: 6-((2-((4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile trichloride
Quality Control & MSDS
Product Details
CAS NO.:1782235-14-6
Appearance:
Molecular Formula:C22H21Cl5N8
Formula Weight:574.72
Melting Point:
Boiling Point:
Flash Point:
Density:
Storage Condition:Store in a tightly closed container, in a cool and dry place.
Description

CHIR-99021, also known as CT99021, is a glycogen synthase kinase 3β (GSK3β) inhibitor that has antiproliferative activity in vitro and in vivo. CHIR-99021 inhibits GSK-3 with IC50 at 7 nM. In a series of carcinoma cell lines, the IC50 of CHIR99021 for proliferation is about 10μM.

252917-06-9 (free base)

1782235-14-6 (3HCl)

2109414-84-6 (2HCl)

1797989-42-4 (HCl)

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