Decernotinib

Catalog NO.:A859400
CAS NO.:944842-54-0
MDL NO.:
EINECS NO.:
Synonyms: (R)-2-((2-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)-2-methyl-N-(2,2,2-trifluoroethyl)butanamide;VX509; VX-509; VX 509 ; VRT831509 ; VRT-831509 ; VRT 831509 . PubChem CID 59422203. Decernotinib; Adelatinib.
Quality Control & MSDS
Product Details
CAS NO.:944842-54-0
Appearance:White powder
Molecular Formula:C18H19F3N6O
Formula Weight:392.39
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Storage Condition:Store in a tightly closed container, in a cool and dry place.
Description

Decernotinib, also known as VX-509 or VRT-831509 or adelatinib, is an oral, selective Janus kinase 3 (JAK3) inhibitor being developed by Vertex. VX-509 may represent a new approach to treating an underlying disease mechanism that triggers inflammation in a number of debilitating diseases, including RA. In immune-mediated diseases, JAK3 is an essential component of the immune signaling cascade. This cascade ultimately contributes to abnormal immune response that results in chronic inflammation and, in the case of RA, irreversible damage to cartilage and bones.

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