(+/-)-Blebbistatin

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For R&D use only.

Catalog NO.：A835747
CAS No. : 674289-55-5
Molecular Formula：C₁₈H₁₆N₂O₂
Molecular Weight： 292.33

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Product Details

CAS Number	674289-55-5	Appearance
Catalog Number	A835747	MDL Number
Molecular Formula	C₁₈H₁₆N₂O₂	Molecular Weight	292.33
Boiling Point		Melting Point
Flash Point		Density
Synonyms	3a-Hydroxy-6-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]chinolin-4-on
Storage Condition	Store in a tightly closed container,in a cool and dry place

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Description

Cell-permeable. A selective inhibitor of non-muscle myosin II ATPases. It rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC₅₀ = 0.5-5.0 μM), while weakly inhibiting smooth muscle myosin (IC₅₀ = 80 μM). Through these effects, blebbistatin reversibly blocks apoptosis-related bleb formation, directed cell migration and cytokinesis in vertebrate cells.

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