1,2-O-(1-methylethylidene)-4-C- [(phenylmethoxy)methyl]-3-O- (phenylmethyl)-L-Lyxofuranose

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Catalog NO.：A848360
CAS No. : 153186-10-8
Molecular Formula：C₂₃H₂₈O₆
Molecular Weight： 400.46

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Quality Control&SDS

SDS COA HPLC/GC NMR

Product Details

CAS Number	153186-10-8	Appearance	Off-White powder
Catalog Number	A848360	MDL Number	MFCD20269093
Molecular Formula	C₂₃H₂₈O₆	Molecular Weight	400.46
Boiling Point		Melting Point
Flash Point		Density
Synonyms	1,2-O-(1-methylethylidene)-4-C-[(phenylmethoxy)methyl]-3-O-(phenylmethyl)-β-L-Lyxofuranose;((3aR,5R,6S,6aR)-6-(benzyloxy)-5-(benzyloxymethyl)-2,2-dimethyl-dihydro-5H-furo[2,3-d][1,3]dioxol-5-yl)methanol
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302;H315;H319;H335	Class
Precautionary Statements	P261;P305+P351+P338	Packing Group

Description

Mibefradil, also known as Ro 405967 or Ro 40-5967, is a drug for the treatment of hypertension and chronic angina pectoris. It belongs to a group known as calcium channel blockers. The mechanism of action of mibefradil is characterized by the selective blockade of transient, low-voltage-activated (T-type) calcium channels over long-lasting, high-voltage-activated (L-type) calcium channels, which is probably responsible for many of its unique properties. It is nonselective. On June 8, 1998, Roche announced the voluntary withdrawal of the drug from the market, one year after approval by the FDA, due to the potential for drug interactions, some of them deadly, which may occur when it is taken together with some other medications.

116644-53-2 (free base)

116666-63-8 (2HCl)

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P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
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P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
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P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
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P370 + P378	In case of fire: Use … for extinction.
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P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
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