PF-431396,717906-29-1-Amadis Chemical

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[CAS No.717906-29-1] A866364 PF-431396 97%

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Catalog No. A866364

Cas No.: 717906-29-1

Molecular Formula: C₂₂H₂₁F₃N₆O₃S

Molecular Weight: 506.50

MDL No: MFCD16038300

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Quality Control of [717906-29-1]

NMR

CNMR

HPLC

LC-MS

Related Doc. of [717906-29-1]

SDS

Specification

MOL

SDF

Product Details [717906-29-1]

Synonyms: N-Methyl-N-[2-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]methanesulfonamide

Appearance:

Melting point:

Boiling point:

Flash point:

Storage: Store in 2-8°C for long term (months)

Pubchem ID: 11598628

Smiles: CS(=O)(N(C)C1=CC=CC=C1CNC2=NC(NC3=CC4=C(NC(C4)=O)C=C3)=NC=C2C(F)(F)F)=O

Inchi: InChI=1S/C22H21F3N6O3S/c1-31(35(2,33)34)18-6-4-3-5-13(18)11-26-20-16(22(23,24)25)12-27-21(30-20)28-15-7-8-17-14(9-15)10-19(32)29-17/h3-9,12H,10-11H2,1-2H3,(H,29,32)(H2,26,27,28,30)

InchiKey: POJZIZBONPAWIV-UHFFFAOYSA-N

Safety [717906-29-1]

Pictogram:

Signal word: Warning

UN No.:

Danger Category:

Packing Group:

Hazard statements: H302;H315;H319;H335

Precautionary statements: P261;P305+P351+P338

Literatures [717906-29-1]

Sorry, the literature is not available.

Similar of [717906-29-1]

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Reason:Inhibitors/Agonists

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Reason:Inhibitors/Agonists

Description [717906-29-1]

PF-431396 is a potent and selective focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor (IC50 values are 2 and 11 nM respectively).

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