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  • Catalog NO.:A10467
  • CAS No. : 879085-55-9
  • Molecular Formula:C19H14Cl2N2O3S
  • Molecular Weight: 421.30
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Product Details

CAS Number 879085-55-9 Appearance
Catalog Number A10467 MDL Number MFCD12407408
Molecular Formula C19H14Cl2N2O3S Molecular Weight 421.30
Boiling Point 561.6°C at 760 mmHg Melting Point
Flash Point Density
Synonyms 2-Chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide
Storage Condition Store in a tightly closed container,in a cool and dry place


GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302-H315-H319-H335 Class
Precautionary Statements P261-P305+P351+P338 Packing Group


Vismodegib, also known as GDC-0449 or RG3616, is a hedgehog antagonist, is also a n orally bioavailable small molecule with potential antineoplastic activity. Hedgehog antagonist GDC-0449 targets the Hedgehog signaling pathway, blocking the activities of the Hedgehog-ligand cell surface receptors PTCH and/or SMO and suppressing Hedgehog signaling.

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