Ademetionine 1,4-butanedisulfonate

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For R&D use only.

Catalog NO.：A897255
CAS No. : 101020-79-5
Molecular Formula：C₁₅H₂₃N₆O₅S^.₂C₄H₁₀O₆S₂^.C₄H₈O₆S₂
Molecular Weight： 1451.62

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Product Details

CAS Number	101020-79-5	Appearance	White powder
Catalog Number	A897255	MDL Number	MFCD11111819
Molecular Formula	C₁₅H₂₃N₆O₅S^.₂C₄H₁₀O₆S₂^.C₄H₈O₆S₂	Molecular Weight	1451.62
Boiling Point		Melting Point	125-135°C
Flash Point		Density
Synonyms	S-Adenosylmethionine 1,4-butanedisulfonate; (3S)-5'-[(3-Amino-3-carboxypropyl)methylsulfonio]-5'-deoxy-adenosine 1,4-butanedisulfonate 1,4-butanedisulfonate (2:1:2);S-Adenosylmethione-1,4-butanedisulfonate
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number	Not hazmat
Hazard Statements	H315; H319; H335	Class
Precautionary Statements	P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501	Packing Group

Description

ABT-737 is an orally available inhibitor of the nuclear enzymes poly(ADP-ribose) polymerase (PARP) 1 and 2, with potential antineoplastic activity. Upon administration, ABT-767 selectively binds to PARP 1 and 2, thereby preventing repair of damaged DNA via the base excision repair (BER) pathway. This agent enhances the accumulation of DNA strand breaks and promotes genomic instability eventually leading to apoptosis. ABT-767 may enhance the cytotoxicity of DNA-damaging agents and reverse tumor cell chemo- and radioresistance.

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P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
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P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
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P337 + P313	IF eye irritation persists: Get medical advice/attention.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire: Use … for extinction.
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P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
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