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  • Catalog NO.:A848804
  • CAS No. : 75059-22-2
  • Molecular Formula:C10H12FN5O3
  • Molecular Weight: 269.23
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Product Details

CAS Number 75059-22-2 Appearance White powder
Catalog Number A848804 MDL Number MFCD20134043
Molecular Formula C10H12FN5O3 Molecular Weight 269.23
Boiling Point 628.6°C at 760 mmHg Melting Point
Flash Point Density
Synonyms (2R,3S,4S,5R)-2-(6-amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol
Storage Condition Store in a tightly closed container,in a cool and dry place


GHS Pictogram
Signal Word UN Number
Hazard Statements H302-H315-H319-H332-H335 Class
Precautionary Statements P280-P305+P351+P338-P310 Packing Group


FIPI is a potent and selective phospholipase D inhibitor. FIPI attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. FIPI rapidly blocks in vivo PA production with subnanomolar potency. We were surprised to find that several biological processes blocked by 1-butanol are not affected by FIPI, suggesting the need for re-evaluation of proposed FIPI does inhibit PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis, indicating potential utility for it as a therapeutic for autoimmunity and cancer metastasis.

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