For R&D use only.


  • Catalog NO.:A871649
  • CAS No. : 501437-28-1
  • Molecular Formula:C19H23F2N5O2
  • Molecular Weight: 391.42
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Product Details

CAS Number 501437-28-1 Appearance Off-White powder
Catalog Number A871649 MDL Number MFCD11223662
Molecular Formula C19H23F2N5O2 Molecular Weight 391.42
Boiling Point 579.3°C at 760 mmHg Melting Point
Flash Point Density
Synonyms 2-((3,5-Difluoro-4-hydroxyphenyl)amino)-8-isopentyl-5,7-dimethyl-7,8-dihydropteridin-6(5H)-one
Storage Condition Store in a tightly closed container,in a cool and dry place


GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302-H315-H319-H335 Class
Precautionary Statements P261-P305+P351+P338 Packing Group


FIPI is a potent and selective phospholipase D inhibitor. FIPI attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. FIPI rapidly blocks in vivo PA production with subnanomolar potency. We were surprised to find that several biological processes blocked by 1-butanol are not affected by FIPI, suggesting the need for re-evaluation of proposed FIPI does inhibit PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis, indicating potential utility for it as a therapeutic for autoimmunity and cancer metastasis.

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