- Catalog NO.：A856857
- CAS No. : 923978-27-2
- Molecular Formula：C22H24O4S
- Molecular Weight： 384.49
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|CAS Number||923978-27-2||Appearance||Yellow crystalline solid|
|Catalog Number||A856857||MDL Number||MFCD27987940|
|Molecular Formula||C22H24O4S||Molecular Weight||384.49|
|Boiling Point||569.0±50.0°C at 760 mmHg||Melting Point|
|Synonyms||Propanoic acid, 2-[2,6-dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methyl-|
|Storage Condition||Store in a tightly closed container,in a cool and dry place|
|Signal Word||Warning||UN Number|
|Precautionary Statements||P261-P305+P351+P338||Packing Group|
CZC24832 is the first selective inhibitor of phosphoinositide 3-kinase γ (PI3Kγ) with efficacy in in vitro and in vivo models of inflammation. Extensive target- and cell-based profiling of CZC24832 revealed regulation of interleukin-17-producing T helper cell (T(H)17) differentiation by PI3Kγ, thus reinforcing selective inhibition of PI3Kγ as a potential treatment for inflammatory and autoimmune diseases.