Elafibranor (GFT505)

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For R&D use only.

Catalog NO.：A856857
CAS No. : 923978-27-2
Molecular Formula：C₂₂H₂₄O₄S
Molecular Weight： 384.49

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Quality Control&SDS

SDS COA HPLC/GC LC-MS/GC-MS NMR

Product Details

CAS Number	923978-27-2	Appearance	Yellow crystalline solid
Catalog Number	A856857	MDL Number	MFCD27987940
Molecular Formula	C₂₂H₂₄O₄S	Molecular Weight	384.49
Boiling Point	569.0±50.0°C at 760 mmHg	Melting Point
Flash Point		Density
Synonyms	(E)-2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxoprop-1-en-1-yl)phenoxy)-2-methylpropanoic acid
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302-H315-H319-H335	Class
Precautionary Statements	P261-P305+P351+P338	Packing Group

Description

CZC24832 is the first selective inhibitor of phosphoinositide 3-kinase γ (PI3Kγ) with efficacy in in vitro and in vivo models of inflammation. Extensive target- and cell-based profiling of CZC24832 revealed regulation of interleukin-17-producing T helper cell (T(H)17) differentiation by PI3Kγ, thus reinforcing selective inhibition of PI3Kγ as a potential treatment for inflammatory and autoimmune diseases.

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