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Elafibranor (GFT505)

  • Catalog NO.:A856857
  • CAS No. : 923978-27-2
  • Molecular Formula:C22H24O4S
  • Molecular Weight: 384.49
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Product Details

CAS Number 923978-27-2 Appearance Yellow crystalline solid
Catalog Number A856857 MDL Number MFCD27987940
Molecular Formula C22H24O4S Molecular Weight 384.49
Boiling Point 569.0±50.0°C at 760 mmHg Melting Point
Flash Point Density
Synonyms (E)-2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxoprop-1-en-1-yl)phenoxy)-2-methylpropanoic acid
Storage Condition Store in a tightly closed container,in a cool and dry place


GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302-H315-H319-H335 Class
Precautionary Statements P261-P305+P351+P338 Packing Group


CZC24832 is the first selective inhibitor of phosphoinositide 3-kinase γ (PI3Kγ) with efficacy in in vitro and in vivo models of inflammation. Extensive target- and cell-based profiling of CZC24832 revealed regulation of interleukin-17-producing T helper cell (T(H)17) differentiation by PI3Kγ, thus reinforcing selective inhibition of PI3Kγ as a potential treatment for inflammatory and autoimmune diseases.

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Elafibranor (GFT505)
(E)-2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxoprop-1-en-1-yl)phenoxy)-2-methylpropanoic acid