Cilofexor(GS-9674)

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For R&D use only.

Catalog NO.：A927993
CAS No. : 1418274-28-8
Molecular Formula：C₂₈H₂₂Cl₃N₃O₅
Molecular Weight： 586.85

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Quality Control&SDS

SDS COA HPLC/GC LC-MS/GC-MS NMR

Product Details

CAS Number	1418274-28-8	Appearance	Off-white powder
Catalog Number	A927993	MDL Number
Molecular Formula	C₂₈H₂₂Cl₃N₃O₅	Molecular Weight	586.85
Boiling Point		Melting Point
Flash Point		Density
Synonyms	2-[3-[2-Chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-4-pyridinecarboxylic acid
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302-H315-H319-H335	Class
Precautionary Statements	P261-P305+P351+P338	Packing Group

Description

Cilofexor (GS-9674) is a potent, selective and orally active nonsteroidal FXR agonist with an EC50 43 nM. Cilofexor has anti-inflammatory and antifibrotic effects. Cilofexor has the potential for primary sclerosing cholangitis (PSC) and nonalcoholic steatohepatitis (NASH) treatment.

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P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
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P337 + P313	IF eye irritation persists: Get medical advice/attention.
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P370 + P378	In case of fire: Use … for extinction.
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