3-Deazaadenosine (hydrochloride)

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For R&D use only.

Catalog NO.：A946953
CAS No. : 86583-19-9
Molecular Formula：C₁₁H₁₅ClN₄O₄
Molecular Weight： 302.72

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Quality Control&SDS

SDS COA NMR

Product Details

CAS Number	86583-19-9	Appearance	Off-white powder
Catalog Number	A946953	MDL Number
Molecular Formula	C₁₁H₁₅ClN₄O₄	Molecular Weight	302.72
Boiling Point		Melting Point
Flash Point		Density
Synonyms	(2R,3R,4S,5R)-2-(4-AMino-1H-iMidazo[4,5-c]pyridin-1-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol hydrochloride
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302;H315;H319;H335	Class
Precautionary Statements	P261;P305+P351+P338	Packing Group

Description

BMS-582949 is a potent and selective P38 mitogen-activated protein kinase (P38 MAPK) inhibitor. BMS-582949 is currently under Phase II clinical trials for the treatment of inflammatory diseases. One clinical study showed that, in stable atherosclerosis, 12 weeks of treatment with BMS-582949 did not reduce arterial inflammation or hs-CRP compared to placebo, whereas intensification of statin therapy significantly decreased arterial inflammation. p38α MAP kinase plays a crucial role in regulating the biosynthesis of many inflammatory cytokines including TNFα and IL-1β.

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