For R&D use only.

TDI-10229

  • Catalog NO.:A950678
  • CAS No. : 2810887-45-5
  • Molecular Formula:C16H16ClN5
  • Molecular Weight: 313.78
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Quality Control&SDS
SDS COA NMR

Product Details

CAS Number 2810887-45-5 Appearance White powder
Catalog Number A950678 MDL Number MFCD34567340
Molecular Formula C16H16ClN5 Molecular Weight 313.78
Boiling Point Melting Point
Flash Point Density
Synonyms 4-(4-Benzyl-1,5-dimethyl-1H-pyrazol-3-yl)-6-chloropyrimidin-2-amine
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302;H315;H319;H335 Class
Precautionary Statements P261;P305+P351+P338 Packing Group

Description

GSK2334470 is a potent 3-phosphoinositide-dependent protein kinase (PDK1) inhibitor (IC50 ~ 10 nM), which does not suppress the activity of 93 other protein kinases including 13 AGC-kinases most related to PDK1 at 500-fold higher concentrations. GSK2334470 also inhibited T-loop phosphorylation and activation of Akt. GSK2334470 will be a useful tool for delineating the roles of PDK1 in biological processes.

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TDI-10229
4-(4-Benzyl-1,5-dimethyl-1H-pyrazol-3-yl)-6-chloropyrimidin-2-amine