6,7-Dichloroquinoxaline-5,8-dione
- Catalogo NO.:A950598
- Numero CAS : 102072-82-2
- Formula molecolare:C8H2Cl2N2O2
- Peso molecolare: 229.02
Nota*
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Inchiesta di massa
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Controllo di qualità&SDS
SDS
Dettagli del prodotto
Numero CAS | 102072-82-2 | Aspetto | |
Numero di catalogo | A950598 | Numero MDL | |
Formula molecolare | C8H2Cl2N2O2 | Peso molecolare | 229.02 |
Punto di ebollizione | Punto di fusione | ||
Punto d'infiammabilità | Densità | ||
Sinonimi | 6,7-Dichloroquinoxaline-5,8-dione | ||
Condizioni di conservazione | Store in a tightly closed container,in a cool and dry place |
Sicurezza
Pittogramma GHS | |||
AVVERTENZA | Warning | Numero ONU | |
Dichiarazioni di pericolo | H302;H315;H319;H335 | Classe | |
Consigli di prudenza | P261;P305+P351+P338 | Gruppo di imballaggio |
Descrizione
BAY 87-2243 is a highly potent and selective inhibitor of hypoxia-induced gene activation, which has antitumor activities by inhibition of mitochondrial complex I. BAY 87-2243 mproves local tumor control after fractionated irradiation in a schedule-dependent manner in head and neck human xenografts. BAY-87-2243 markedly decreased nuclear HIF-1α expression and pimonidazole hypoxic fraction already after 3 days of drug treatment. BAY-87-2243 prior to RT significantly reduced TCD50 from 123 to 100 Gy (p=0.037). Additional BAY-87-2243 application during RT did not decrease TCD50. |