，BRD-6929，849234-64-6-Amadis Chemical

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[CAS No.849234-64-6] A1039233 BRD-6929 97%

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Catalog No.: A1039233

Cas No.: 849234-64-6

Molecular Formula: C₁₉H₁₇N₃O₂S

Molecular Weight: 351.42

MDL NO:

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Quality Control of [849234-64-6]

NMR

CNMR

HPLC

LC-MS

Related Doc. of[849234-64-6]

SDS

Specification

MOL

SDF

基础信息 [849234-64-6]

同义词: 4-acetamido-N-(2-amino-5-(thiophen-2-yl)phenyl)benzamide

Appearance:

存储要求: Store in 2-8°C for long term (months)

沸点:

熔点:

闪点:

Pubchem ID:

Smiles: O=C(NC1=C(C=CC(C2=CC=CS2)=C1)N)C3=CC=C(C=C3)NC(C)=O

InchiKey: ABZSPJVXTTUFAA-UHFFFAOYSA-N

Inchi: InChI=1S/C19H17N3O2S/c1-12(23)21-15-7-4-13(5-8-15)19(24)22-17-11-14(6-9-16(17)20)18-3-2-10-25-18/h2-11H,20H2,1H3,(H,21,23)(H,22,24)

安全信息 [849234-64-6]

GHS Pictogram:

Signal Word: Warning

Class:

Precautionary Statements: P261;P305+P351+P338

UN No.:

Hazard Statements: H302;H315;H319;H335

包装等级:

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产品详情 [849234-64-6]

BRD6929 is a histone deacetylase 1 (HDAC1) and HDAC2 inhibitor (IC50s = 0.04 and 0.1 µM, respectively, for the recombinant human enzymes). It is selective for HDAC1 and HDAC2 over HDAC3 and HDAC8 (IC50s = >20 µM for both). BRD6929 inhibits proliferation of HCT116 human colon cancer cells but not non-cancerous human mammary epithelial cells (HMECs; IC50s = 4 and >50 µM, respectively)

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