BMS-345541 hydrochloride

Catalog NO.:A904000
CAS NO.:547757-23-3
MDL NO.:
EINECS NO.:
Synonyms: N1-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)ethane-1,2-diamine hydrochloride
Quality Control & MSDS
Product Details
CAS NO.:547757-23-3
Appearance:
Molecular Formula:C14H18ClN5
Formula Weight:291.78
Melting Point:
Boiling Point:
Flash Point:
Density:
Storage Condition:Store in a tightly closed container, in a cool and dry place.
Description

BMS 345541 is a selective allosteric inhibitor of IKK (IC50 values are 0.3 and 4.0 μM for IKKβ and IKKα respectively). It attenuates LPS-induced cytokine production in vitro and blocks NFκB dependent transcription in mice. BMS 345541 also suppresses joint destruction in a mouse model of arthritis.

445430-58-0 (free base) 

547757-23-3 (HCl)

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