2-chloro-5,6-difluorobenzo[d]thiazole

Catalog NO.:A902883
CAS NO.:960535-39-1
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Product Details
CAS NO.:960535-39-1
Appearance:Light yellow solid
Molecular Formula:C7H2ClF2NS
Formula Weight:205.61
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Storage Condition:Store in a tightly closed container, in a cool and dry place.
Description

Niraparib, also known as MK4827, is an orally active, potent and selective poly(ADP-Ribose) polymerase (PARP) inhibitor that radiosensitizes human lung and breast cancer cells. Niraparib inhibits PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM respectively. Niraparib is currently in Phase 3 clinical trials for ovarian cancer and BRCA+ breast cancer.

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