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[CAS No.1624306-20-2] A1256987 Gepotidacin mesylate dihydrate 98%
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Similar of [1624306-20-2]
Gepotidacin hydrochloride
Reason:Inhibitors/Agonists
Gepotidacin
Reason:Inhibitors/Agonists
Description [1624306-20-2]

Gepotidacin, also known as GSK-2140944, is a potent Type II DNA topoisomerase inhibitor. Gepotidacin is a novel antibacterial drug candidate. Gepotidacin Demonstrates Absence of Fluoroquinolone-Like Arthropathy in Juvenile Rats. Gepotidacin is efficacious in a nonhuman primate model of pneumonic plague. When tested against Gram-negative (n = 333) and Gram-positive (n = 225) anaerobes by agar dilution, gepotidacin inhibited 90% of isolates at concentrations of 4 and 2 μg/mL, respectively.

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