Calcipotriol Impurity C

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For R&D use only.

Catalog NO.：A907396
CAS No. : 113082-99-8
Molecular Formula：C₂₇H₄₀O₃
Molecular Weight： 412.60

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Product Details

CAS Number	113082-99-8	Appearance
Catalog Number	A907396	MDL Number
Molecular Formula	C₂₇H₄₀O₃	Molecular Weight	412.60
Boiling Point		Melting Point
Flash Point		Density
Synonyms	(1S,3S,5E)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-Cyclopropyl-4-hydroxy-1-Methyl-2-buten-1-yl]octahydro-7a-Methyl-4H-inden-4-ylidene]ethylidene]-4-Methylene-1,3-cyclohexanediol
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Danger	UN Number	2811
Hazard Statements	H300	Class	6.1
Precautionary Statements	P264-P301+P310	Packing Group	Ⅱ

Description

Navitoclax, also known as ABT-263, is an orally bioavailable, synthetic small-molecule antagonist of a subset of the B-cell leukemia 2 (Bcl-2) family of proteins with potential antineoplastic activity. ABT-263 selectively binds to apoptosis suppressor proteins Bcl-2, Bcl-XL, and Bcl-w and prevents their binding to the apoptotic effectors Bax and Bak proteins, which may trigger apoptosis in tumor cells overexpressing Bcl-2, Bcl-XL, and Bcl-w.

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