For R&D use only.

1-Methyl-7-nitroisatoic anhydride

  • Catalog NO.:A918313
  • CAS No. : 73043-80-8
  • Molecular Formula:C9H6N2O5
  • Molecular Weight: 222.15
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Product Details

CAS Number 73043-80-8 Appearance
Catalog Number A918313 MDL Number MFCD18432729
Molecular Formula C9H6N2O5 Molecular Weight 222.15
Boiling Point 395.4±44.0°C at 760 mmHg Melting Point
Flash Point Density
Synonyms 7-nitro-1-methyl-1H-benzo[d][1,3]oxazine-2,4-dione
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302 Class
Precautionary Statements P280-P305+P351+P338 Packing Group

Description

Alpelisib, also known as BLY719, is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BYL719 specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway, thereby inhibiting the activation of the PI3K signaling pathway. This may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis. Dysregulated PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents. Check for active clinical trials or closed clinical trials using this agent.

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1-Methyl-7-nitroisatoic anhydride
7-nitro-1-methyl-1H-benzo[d][1,3]oxazine-2,4-dione