Tropifexor

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For R&D use only.

Catalog NO.：A903437
CAS No. : 1383816-29-2
Molecular Formula：C₂₉H₂₅F₄N₃O₅S
Molecular Weight： 603.59

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Quality Control&SDS

SDS COA NMR

Product Details

CAS Number	1383816-29-2	Appearance	White powder
Catalog Number	A903437	MDL Number	MFCD31693060
Molecular Formula	C₂₉H₂₅F₄N₃O₅S	Molecular Weight	603.59
Boiling Point		Melting Point
Flash Point		Density
Synonyms	rel-2-((1R,3r,5S)-3-((5-cyclopropyl-3-(2-(trifluoromethoxy)phenyl)isoxazol-4-yl)methoxy)-8-azabicyclo[3.2.1]octan-8-yl)-4-fluorobenzo[d]thiazole-6-carboxylic acid
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302-H315-H319-H335	Class
Precautionary Statements	P261-P301+P312-P302+P352-P304+P340-P305+P351+P338	Packing Group

Description

Tropifexor, also known as LJN452, is a farnesoid X receptor agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH). Potent in vivo activity was demonstrated in rodent PD models by measuring the induction of FXR target genes in various tissues. Tropifexor has advanced into phase 2 human clinical trials in patients with NASH and PBC.

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H200	Explosives (Unstable Explosive)
H201	Explosives （Div 1.1)
H202	Explosives (Div 1.2)
H203	Explosives (Div 1.3)
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H330	Acute toxicity,inhalation (Category 1, 2)
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H333	Acute toxicity,inhalation (Category 5)
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H340	Germ cell mutagenicity (Category 1A, 1B)
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H400	Hazardous to the aquatic environment, acute hazard (Category 1)
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