For R&D use only.

Triisopropylsilyl Trifluoromethanesulfonate

  • Catalog NO.:A839932
  • CAS No. : 80522-42-5
  • Molecular Formula:C10H21F3O3SSi
  • Molecular Weight: 306.42
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Quality Control&SDS
SDS COA NMR

Product Details

CAS Number 80522-42-5 Appearance Colorless liquid
Catalog Number A839932 MDL Number MFCD00009913
Molecular Formula C10H21F3O3SSi Molecular Weight 306.42
Boiling Point 252.9°C at 760 mmHg Melting Point
Flash Point 213 °F Density
Synonyms Trifluoromethanesulfonic Acid Triisopropylsilyl Ester
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Danger UN Number 3265
Hazard Statements H314 Class 8
Precautionary Statements P280-P305+P351+P338-P310 Packing Group

Description

Alpelisib, also known as BLY719, is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BYL719 specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway, thereby inhibiting the activation of the PI3K signaling pathway. This may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis. Dysregulated PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents. Check for active clinical trials or closed clinical trials using this agent.

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Triisopropylsilyl Trifluoromethanesulfonate
Trifluoromethanesulfonic Acid Triisopropylsilyl Ester