ML 348
- Catalog NO.:A903369
- CAS No. : 899713-86-1
- Molecular Formula:C18H17ClF3N3O3
- Molecular Weight: 415.79
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
Product Details
CAS Number | 899713-86-1 | Appearance | |
Catalog Number | A903369 | MDL Number | |
Molecular Formula | C18H17ClF3N3O3 | Molecular Weight | 415.79 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | N-[2-Chloro-5-(trifluoromethyl)phenyl]-4-(2-furanylcarbonyl)-1-piperazineacetamide;CID 3238952; SID 160654487;ML348 | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
ML348, also known as CID 3238952; SID 160654487, is a reversible LYPLA1 inhibitor with an IC50 value of 210 nM. Multiple oncogenes, including HRAS and SRC, require palmitoylation for malignant transformation. Lysophospholipase 1 (LYPLA1) has been identified as a candidate protein palmitoyl thioesterase responsible for HRAS depalmitoylation in mammalian cells. |