7-Iodo-1H-benzo[d][1,3]oxazine-2,4-dione

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For R&D use only.

Catalog NO.：A849168
CAS No. : 115081-94-2
Molecular Formula：C₈H₄InO₃
Molecular Weight： 289.03

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Product Details

CAS Number	115081-94-2	Appearance
Catalog Number	A849168	MDL Number	MFCD11519432
Molecular Formula	C₈H₄InO₃	Molecular Weight	289.03
Boiling Point		Melting Point
Flash Point		Density
Synonyms	7-Iodo-1H-benzo[d][1,3]oxazine-2,4-dione
Storage Condition	Store in a tightly closed container,in a cool and dry place

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Description

BAY 11-7082 is an inhibitor of κB kinase (IKK) that has pharmacological activities that include anticancer, neuroprotective, and anti-inflammatory effects. BAY 11-7082 strongly suppressed the production of nitric oxide, prostaglandin E(2), and tumor necrosis factor-α and reduced the translocation of p65, major subunit of nuclear factor-κB, and its upstream signaling events such as phosphorylation of IκBα, IKK, and Akt. In addition. Bay 11-7082 induces cell death independent from inhibition of activation of NFκB transcription factors.BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system. Bay 11-7082 induces cell death independent from inhibition of activation of NFκB transcription factors.

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H200	Explosives (Unstable Explosive)
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