Dalfopristin

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Catalog NO.：A900906
CAS No. : 112362-50-2
Molecular Formula：C₃₄H₅₀N₄O₉S
Molecular Weight： 690.85

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Product Details

CAS Number	112362-50-2	Appearance
Catalog Number	A900906	MDL Number
Molecular Formula	C₃₄H₅₀N₄O₉S	Molecular Weight	690.85
Boiling Point		Melting Point
Flash Point		Density
Synonyms	RP 54476;(3R,4R,5E,10E,12E,14S,26R,26aS)-26-[[2-(diethylamino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a- octahydro-14-hydroxy-3-isopropyl-4,12-dimethyl-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]-dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
Storage Condition	Store in a tightly closed container,in a cool and dry place

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Description

Dalfopristin is a semi-synthetic derivative of streptogramin A produced by streptomycetes. Dalfopristin inhibits the early phase of protein synthesis in the bacterial ribosome by binding to the 70S subunit, and also alters the configuration of the ribosome to make it more susceptible for streptogramin B binding. Dalfopristin is used in combination with quinopristin, a streptogramin B derivative. This combination is active against most gram-positive organisms, including Enterococcus faecium, and is also active against some gram-negative organisms and mycoplasma.

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