Ziprasidone Hydrochloride hydrate

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For R&D use only.

Catalog NO.：A807468
CAS No. : 138982-67-9
Molecular Formula：C₂₁H₂₄Cl₂N₄O₂S
Molecular Weight： 467.41

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Product Details

CAS Number	138982-67-9	Appearance
Catalog Number	A807468	MDL Number	MFCD00921885
Molecular Formula	C₂₁H₂₄Cl₂N₄O₂S	Molecular Weight	467.41
Boiling Point	554.8°C at 760 mmHg	Melting Point
Flash Point		Density
Synonyms	5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one Hydrochloride Monohydrate
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Danger	UN Number	2811Ⅲ
Hazard Statements	H317-H373	Class	6.1
Precautionary Statements	P260-P280	Packing Group

Description

Ziprazidone is approved for the treatment of schizophrenia, and acute mania and mixed states associated with bipolar disorder. Its intramuscular injection form is approved for acute agitation in schizophrenic patients for whom treatment with just ziprasidone is appropriate. The mechanism of action of ziprasidone, as with other drugs having efficacy in schizophrenia, is unknown. However, it has been proposed that this drug's efficacy in schizophrenia is mediated through a combination of dopamine type 2 (D2) and serotonin type 2 (5HT2) antagonism. As with other drugs having efficacy in bipolar disorder, the mechanism of action of ziprasidone in bipolar disorder is unknown.

199191-69-0 (Mesylate Trihydrate);

122883-93-6 (HCl salt);

138982-67-9 (HCl hydrate);

146939-27-7 (free base)

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