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tert-Butyl 4,7-diazaspiro[2.5]octane-4-carboxylate
- Catalog NO.:A867260
- CAS No. : 674792-08-6
- Molecular Formula:C11H20N2O2
- Molecular Weight: 212.29
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 674792-08-6 | Appearance | White solid |
Catalog Number | A867260 | MDL Number | MFCD08685932 |
Molecular Formula | C11H20N2O2 | Molecular Weight | 212.29 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | tert-Butyl 4,7-diazaspiro[2.5]octane-4-carboxylate | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H332-H335 | Class | |
Precautionary Statements | P261-P280-P305+P351+P338 | Packing Group |
Description
Entinostat, also known as MS-275 or SNDX-275, is a potent HDAC inhibitor with potential antineoplastic activity. Entinostat binds to and inhibits histone deacetylase, an enzyme that regulates chromatin structure and gene transcription. This agent appears to exert dose-dependent effects in human leukemia cells including cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1)-dependent growth arrest and differentiation at low drug concentrations; a marked induction of reactive oxygen species (ROS); mitochondrial damage; caspase activation; and, at higher concentrations, apoptosis. |