ML364
- Catalog NO.:A902635
- CAS No. : 1991986-30-1
- Molecular Formula:C24H18F3N3O3S2
- Molecular Weight: 517.54
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 1991986-30-1 | Appearance | Off-white powder |
Catalog Number | A902635 | MDL Number | |
Molecular Formula | C24H18F3N3O3S2 | Molecular Weight | 517.54 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | 2-(4-Methylphenylsulfonamido)-N-(4-phenylthiazol-2-yl)-4-(trifluoromethyl)benzamide | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
ML364 is a selective ubiquitin specific peptidase 2 (USP2) inhibitor (IC50=1.1 μM) with anti-proliferative activity, which direct binds to USP2 (Kd=5.2 μM), induces an increase in cellular cyclin D1 degradation and causes cell cycle arrest. ML364 increases the levels of mitochondrial ROS and decreases in the intracellular content of ATP[1][2]. |