L-Glutamic acid monopotassium salt

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For R&D use only.

Catalog NO.：A813747
CAS No. : 19473-49-5
Molecular Formula：C₅H₈KNO₄
Molecular Weight： 185.21

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Product Details

CAS Number	19473-49-5	Appearance	Light yellow crystalline powder
Catalog Number	A813747	MDL Number	MFCD00035545
Molecular Formula	C₅H₈KNO₄	Molecular Weight	185.21
Boiling Point		Melting Point
Flash Point		Density
Synonyms	L-Glutamic acid monopotassium salt
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302;H315;H319;H335	Class
Precautionary Statements	P261;P305+P351+P338	Packing Group

Description

Navitoclax, also known as ABT-263, is an orally bioavailable, synthetic small-molecule antagonist of a subset of the B-cell leukemia 2 (Bcl-2) family of proteins with potential antineoplastic activity. ABT-263 selectively binds to apoptosis suppressor proteins Bcl-2, Bcl-XL, and Bcl-w and prevents their binding to the apoptotic effectors Bax and Bak proteins, which may trigger apoptosis in tumor cells overexpressing Bcl-2, Bcl-XL, and Bcl-w.

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