7H-Benzo[c]carbazole

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For R&D use only.

Catalog NO.：A846259
CAS No. : 205-25-4
Molecular Formula：C₁₆H₁₁N
Molecular Weight： 217.27

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Product Details

CAS Number	205-25-4	Appearance	Light brown solid
Catalog Number	A846259	MDL Number	MFCD00215940
Molecular Formula	C₁₆H₁₁N	Molecular Weight	217.27
Boiling Point	456.1°C at 760 mmHg	Melting Point
Flash Point		Density
Synonyms	3,4-Benzocarbazole;7-Aza-7H-benzo[c]fluorene
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

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Signal Word	Warning	UN Number
Hazard Statements	H302	Class
Precautionary Statements	P280-P305+P351+P338	Packing Group

Description

BMS-777607, also known as BMS-817378 and ASLAN-002, a Met tyrosine kinase inhibitor, is an inhibitor of MET tyrosine kinase with potential antineoplastic activity. MET tyrosine kinase inhibitor BMS-777607 binds to c-Met protein, or hepatocyte growth factor receptor (HGFR), preventing binding of hepatocyte growth factor (HGF) and disrupting the MET signaling pathway; this agent may induce cell death in tumor cells expressing c-Met. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays an important role in tumor cell proliferation, survival, invasion, and metastasis, and in tumor angiogenesis.

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H200	Explosives (Unstable Explosive)
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