HBX 41108

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For R&D use only.

Catalog NO.：A903088
CAS No. : 924296-39-9
Molecular Formula：C₁₃H₃ClN₄O
Molecular Weight： 266.64

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Product Details

CAS Number	924296-39-9	Appearance
Catalog Number	A903088	MDL Number	MFCD16251537
Molecular Formula	C₁₃H₃ClN₄O	Molecular Weight	266.64
Boiling Point		Melting Point
Flash Point		Density
Synonyms	7-Chloro-9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements		Class
Precautionary Statements		Packing Group

Description

Inhibitor of ubiquitin-specific protease (USP) 7 activity (IC50 = 424 nM). Displays uncompetitive inhibition. Also inhibits USP7-mediated p53 deubiquitination (IC50 = 0.8 μM). Stabilizes p53 and inhibits cancer cell growth; induces p53-dependent apoptosis in p53 wild type and null isogenic cancer cell lines.

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H200	Explosives (Unstable Explosive)
H201	Explosives （Div 1.1)
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H318	Serious eye damage/eye irritation (Category 1)
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H330	Acute toxicity,inhalation (Category 1, 2)
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H340	Germ cell mutagenicity (Category 1A, 1B)
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H400	Hazardous to the aquatic environment, acute hazard (Category 1)
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H420	Hazardous to the ozone layer (Category 1)