Obeticholic acid
- Catalog NO.:A854341
- CAS No. : 459789-99-2
- Molecular Formula:C26H44O4
- Molecular Weight: 420.63
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 459789-99-2 | Appearance | Off-white powder |
Catalog Number | A854341 | MDL Number | MFCD16621104 |
Molecular Formula | C26H44O4 | Molecular Weight | 420.63 |
Boiling Point | 562.9°C at 760 mmHg | Melting Point | |
Flash Point | Density | ||
Synonyms | INT-747;(R)-4-((3R,7R,8S,9S,10S,13R,14S,17R)-6-Ethyl-3,7-dihydroxy-10,13-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
Obeticholic acid is a derivative of cholic acid which acts as a potent and selective FXR (Farnesoid X receptor) agonist (EC₅₀ = 99 nM) displaying anticholeretic activity in an in vivo rat model of cholestasis. Obeticholic acid is 100-fold more potent than the endogenous ligand chenodeoxycholic acid |