5-Fluorouracil

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For R&D use only.

Catalog NO.：A7567
CAS No. : 51-21-8
Molecular Formula：C₄H₃FN₂O₂
Molecular Weight： 130.08

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Product Details

CAS Number	51-21-8	Appearance	White powder
Catalog Number	A7567	MDL Number	MFCD00006018
Molecular Formula	C₄H₃FN₂O₂	Molecular Weight	130.08
Boiling Point	401.4°C at 760 mmHg	Melting Point	282-286 °C (dec.)(lit.)
Flash Point	196.5oC	Density	1.53 g/cm3
Synonyms	5-fluoropyrimidine-2,4(1H,3H)-dione
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Danger	UN Number	2811
Hazard Statements	H301;H351	Class	6.1
Precautionary Statements	P281-P301+P310	Packing Group	Ⅲ

Description

CZC24832 is the first selective inhibitor of phosphoinositide 3-kinase γ (PI3Kγ) with efficacy in in vitro and in vivo models of inflammation. Extensive target- and cell-based profiling of CZC24832 revealed regulation of interleukin-17-producing T helper cell (T(H)17) differentiation by PI3Kγ, thus reinforcing selective inhibition of PI3Kγ as a potential treatment for inflammatory and autoimmune diseases.

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H200	Explosives (Unstable Explosive)
H201	Explosives （Div 1.1)
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H203	Explosives (Div 1.3)
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H318	Serious eye damage/eye irritation (Category 1)
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H330	Acute toxicity,inhalation (Category 1, 2)
H331	Acute toxicity,inhalation (Category 3)
H332	Acute toxicity,inhalation (Category 4)
H333	Acute toxicity,inhalation (Category 5)
H334	Sensitisation, respiratory (Category 1)
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H340	Germ cell mutagenicity (Category 1A, 1B)
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H400	Hazardous to the aquatic environment, acute hazard (Category 1)
H401	Hazardous to the aquatic environment, acute hazard (Category 2)
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