4-(trans-4-AMylcyclohexyl)benzonitrile

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For R&D use only.

Catalog NO.：A833098
CAS No. : 61204-01-1
Molecular Formula：C₁₈H₂₅N
Molecular Weight： 255.40

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Quality Control&SDS

SDS COA NMR

Product Details

CAS Number	61204-01-1	Appearance
Catalog Number	A833098	MDL Number	MFCD00075548
Molecular Formula	C₁₈H₂₅N	Molecular Weight	255.40
Boiling Point	381°C at 760 mmHg	Melting Point	30-55 °C(lit.)
Flash Point	>230 °F	Density	0.97 g/cm3
Synonyms	4-((1s,4r)-4-pentylcyclohexyl)benzonitrile
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H315-H319-H335	Class
Precautionary Statements	P261-P305+P351+P338	Packing Group

Description

Alpelisib, also known as BLY719, is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BYL719 specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway, thereby inhibiting the activation of the PI3K signaling pathway. This may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis. Dysregulated PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents. Check for active clinical trials or closed clinical trials using this agent.

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P301	IF SWALLOWED:
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P370 + P378	In case of fire: Use … for extinction.
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P401	Store …
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P501	Dispose of contents/container to..…
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H200	Explosives (Unstable Explosive)
H201	Explosives （Div 1.1)
H202	Explosives (Div 1.2)
H203	Explosives (Div 1.3)
H204	Explosives (Div 1.4)
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H300	Acute toxicity,oral (Category 1, 2)
H301	Acute toxicity,oral (Category 3)
H302	Acute toxicity,oral (Category 4)
H303	Acute toxicity,oral (Category 5)
H304	Aspiration hazard (Category 1)
H305	Aspiration hazard (Category 2)
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H314	Skin corrosion/irritation (Category 1A, B, C)
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H317	Sensitisation, Skin (Category 1)
H318	Serious eye damage/eye irritation (Category 1)
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H330	Acute toxicity,inhalation (Category 1, 2)
H331	Acute toxicity,inhalation (Category 3)
H332	Acute toxicity,inhalation (Category 4)
H333	Acute toxicity,inhalation (Category 5)
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H371	Specific target organ toxicity, single exposure (Category 2)
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H400	Hazardous to the aquatic environment, acute hazard (Category 1)
H401	Hazardous to the aquatic environment, acute hazard (Category 2)
H402	Hazardous to the aquatic environment, acute hazard (Category 3)
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