For R&D use only.

Lanifibranor

  • Catalog NO.:A903382
  • CAS No. : 927961-18-0
  • Molecular Formula:C19H15ClN2O4S2
  • Molecular Weight: 434.92
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Quality Control&SDS
SDS COA NMR

Product Details

CAS Number 927961-18-0 Appearance Off-white powder
Catalog Number A903382 MDL Number MFCD31619253
Molecular Formula C19H15ClN2O4S2 Molecular Weight 434.92
Boiling Point 690.9±65.0 °C Melting Point 74 - 80 °C
Flash Point Density
Synonyms IVA-337; IVA 337;4-(1-(1,3-Benzothiazol-6-ylsulfonyl)-5-chloro-indol-2-yl)butanoic acid;IVA-337
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302-H315-H319-H335 Class
Precautionary Statements P261-P305+P351+P338 Packing Group

Description

ABT-737 is an orally available inhibitor of the nuclear enzymes poly(ADP-ribose) polymerase (PARP) 1 and 2, with potential antineoplastic activity. Upon administration, ABT-767 selectively binds to PARP 1 and 2, thereby preventing repair of damaged DNA via the base excision repair (BER) pathway. This agent enhances the accumulation of DNA strand breaks and promotes genomic instability eventually leading to apoptosis. ABT-767 may enhance the cytotoxicity of DNA-damaging agents and reverse tumor cell chemo- and radioresistance.

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Lanifibranor
IVA-337; IVA 337;4-(1-(1,3-Benzothiazol-6-ylsulfonyl)-5-chloro-indol-2-yl)butanoic acid;IVA-337