For R&D use only.

Ethene-1,1-diyldibenzene

  • Catalog NO.:A829365
  • CAS No. : 530-48-3
  • Molecular Formula:C14H12
  • Molecular Weight: 180.25
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Product Details

CAS Number 530-48-3 Appearance Light yellow to colorless liquid
Catalog Number A829365 MDL Number MFCD00008583
Molecular Formula C14H12 Molecular Weight 180.25
Boiling Point 270-271°C at 760 mmHg Melting Point 6°C
Flash Point Density 1.02
Synonyms Ethene-1,1-diyldibenzene
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number Not hazmat
Hazard Statements H302-H315-H319-H335 Class
Precautionary Statements P261-P305+P351+P338 Packing Group

Description

Tucatinib, also known as Irbinitinib, ARRY-380 and ONT-380, is a n orally bioavailable inhibitor of the human epidermal growth factor receptor tyrosine kinase ErbB-2 (also called HER2) with potential antineoplastic activity. ErbB-2 inhibitor ARRY-380 selectively binds to and inhibits the phosphorylation of ErbB-2, which may prevent the activation of ErbB-2 signal transduction pathways, resulting in growth inhibition and death of ErbB-2-expressing tumor cells. ErbB-2 is overexpressed in a variety of cancers and plays an important role in cellular proliferation and differentiation.

937263-43-9 (Arry-380)

937265-83-3 (ARRY-380 analog)

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Ethene-1,1-diyldibenzene
Ethene-1,1-diyldibenzene