4,4-Difluorocyclohexanone

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For R&D use only.

Catalog NO.：A816238
CAS No. : 22515-18-0
Molecular Formula：C₆H₈F₂O
Molecular Weight： 134.12

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Product Details

CAS Number	22515-18-0	Appearance
Catalog Number	A816238	MDL Number	MFCD08146635
Molecular Formula	C₆H₈F₂O	Molecular Weight	134.12
Boiling Point	157.4℃ at 760 mmHg	Melting Point
Flash Point	65 ℃(149 ℉)(lit.)	Density
Synonyms	4,4-difluorocyclohexanone
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H315-H319-H335	Class
Precautionary Statements	P261-P305+P351+P338	Packing Group

Description

Pomaglumetad, also known as LY-404,039, is a highly selective agonist for the metabotropic glutamate receptor group II subtypes mGluR2 and mGluR3. Pomaglumetad has potential antipsychotic and anxiolytic effects. LY-404,039 is intended as a treatment for schizophrenia and other psychotic and anxiety disorders by modulating glutamatergic activity and reducing presynaptic release of glutamate at synapses in limbic and forebrain areas relevant to these disorders. The specific binding of LY-404,039 to human cloned mGlu receptors has been found to be highest for mGluR2 (Ki = 149 +/- 11 nM) and relatively high for mGluR3 (Ki = 92 +/-14 nM).

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H200	Explosives (Unstable Explosive)
H201	Explosives （Div 1.1)
H202	Explosives (Div 1.2)
H203	Explosives (Div 1.3)
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H301	Acute toxicity,oral (Category 3)
H302	Acute toxicity,oral (Category 4)
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H318	Serious eye damage/eye irritation (Category 1)
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H330	Acute toxicity,inhalation (Category 1, 2)
H331	Acute toxicity,inhalation (Category 3)
H332	Acute toxicity,inhalation (Category 4)
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H340	Germ cell mutagenicity (Category 1A, 1B)
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H400	Hazardous to the aquatic environment, acute hazard (Category 1)
H401	Hazardous to the aquatic environment, acute hazard (Category 2)
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