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Vorinostat

  • Catalog NO.:A808935
  • CAS No. : 149647-78-9
  • Molecular Formula:C14H20N2O3
  • Molecular Weight: 264.32
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Quality Control&SDS
COA NMR

Product Details

CAS Number 149647-78-9 Appearance Off-white powder
Catalog Number A808935 MDL Number MFCD00945317
Molecular Formula C14H20N2O3 Molecular Weight 264.32
Boiling Point Melting Point 159-168°C
Flash Point Density
Synonyms N1-hydroxy-N8-phenyl-octanediamide
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Danger UN Number Not hazmat
Hazard Statements H341; H360 Class
Precautionary Statements P201; P202; P281; P308+P313; P405; P501 Packing Group

Description

Tavaborole, also known as AN-2690 (trade name Kerydin) is a topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed. Tavaborole began its Phase 3 trials in December 2010 and was approved in July 2014. Tavaborole inhibits an essential fungal enzyme, Leucyl-tRNA synthetase, or LeuRS, required for protein synthesis. The inhibition of protein synthesis leads to termination of cell growth and cell death, eliminating the fungal infection. No treatment-related systemic side effects were observed in any of its clinical trials.

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Vorinostat
N1-hydroxy-N8-phenyl-octanediamide