tert-Butyl (3-oxopropyl)carbamate

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For R&D use only.

Catalog NO.：A852347
CAS No. : 58885-60-2
Molecular Formula：C₈H₁₅NO₃
Molecular Weight： 173.21

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Quality Control&SDS

SDS COA NMR

Product Details

CAS Number	58885-60-2	Appearance	Colorless oily liquid
Catalog Number	A852347	MDL Number	MFCD08059952
Molecular Formula	C₈H₁₅NO₃	Molecular Weight	173.21
Boiling Point		Melting Point
Flash Point		Density
Synonyms	(3-Oxopropyl)carbamic acid tert-butyl ester
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302-H315-H319-H332-H335	Class
Precautionary Statements	P233-P260-P261-P264-P270-P271-P280-P301+P312-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P330-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501	Packing Group

Description

Mertansine refers to the thiol-containing maytansinoid, DM1 (N2’-deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) attached to a monoclonal antibody through reaction of the thiol group with the SPP (N-succinimidyl 4-(2-pyridyldithio)) linker to create an antibody-drug conjugate or ADC. Experimental ADCs with the SPP-DM1 design include lorvotuzumab mertansine. DM1 can also be linked to an antibody using the SMCC (4-(3-mercapto-2,5-dioxo-1-pyrrolidinylmethyl)-cylohexanecarboxylic acid) linker, in which case the International Nonproprietary Name of the conjugate formed contains the word emtansine. DM1 and its attachment via these linkers result from ImmunoGen Inc research. Trastuzumab emtansine (T-DM1) is an anti-HER2/neu antibody-drug conjugate.

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My Tracks: tert-Butyl (3-oxopropyl)carbamate

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H200	Explosives (Unstable Explosive)
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