3'-amino-2',3'-dideoxycytidine

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For R&D use only.

Catalog NO.：A840798
CAS No. : 84472-90-2
Molecular Formula：C₉H₁₄N₄O₃
Molecular Weight： 226.24

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Product Details

CAS Number	84472-90-2	Appearance
Catalog Number	A840798	MDL Number	MFCD00870894
Molecular Formula	C₉H₁₄N₄O₃	Molecular Weight	226.24
Boiling Point		Melting Point
Flash Point		Density
Synonyms	4-amino-1-((2R,4S,5S)-4-amino-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
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Hazard Statements		Class
Precautionary Statements		Packing Group

Description

FIPI is a potent and selective phospholipase D inhibitor. FIPI attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. FIPI rapidly blocks in vivo PA production with subnanomolar potency. We were surprised to find that several biological processes blocked by 1-butanol are not affected by FIPI, suggesting the need for re-evaluation of proposed FIPI does inhibit PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis, indicating potential utility for it as a therapeutic for autoimmunity and cancer metastasis.

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