Ethyl 1-(2-fluorobenzyl)-1h-pyrazolo[3,4-b]pyridine-3-carboxylate

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For R&D use only.

Catalog NO.：A877529
CAS No. : 256376-59-7
Molecular Formula：C₁₆H₁₄FN₃O₂
Molecular Weight： 299.30

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Product Details

CAS Number	256376-59-7	Appearance
Catalog Number	A877529	MDL Number	MFCD20268230
Molecular Formula	C₁₆H₁₄FN₃O₂	Molecular Weight	299.30
Boiling Point		Melting Point
Flash Point		Density
Synonyms	1-Piperidinepropanoic acid, 3-(ethoxycarbonyl)-, ethyl ester; 1-(2-ethoxycarbonyl-ethyl)-piperidine-3-carboxylic acid ethyl ester; AGN-PC-00BP2I; SureCN935060; 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid ethyl ester; 1-(2-Aethoxycarbonyl-aethyl)-piperidin-3-carbonsaeure-aethylester; ACMC-20msqy; CTK0F6237; ethyl 1-(2-ethoxycarbonyl)ethylpiperidine-3-carboxylate; ethyl 1-[2-(ethoxycarbonyl)ethyl]-3-piperidinecarboxylate; ethyl 1-[2-(Ethoxycarbonyl)ethyl]-3-piperidinecarboxylate; ethyl 3-[1-(3-carbethoxy)-piperidinyl]propionate;
Storage Condition	Store in a tightly closed container,in a cool and dry place

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Description

Potent, cell-permeable inhibitor of Sonic hedgehog (Shh) signaling; high affinity antagonist of smoothened activity (KD = 1.2 nM). Inhibits smoothened agonist effects with an IC50 of 20 nM (in Shh-LIGHT2 cells).

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