For R&D use only.

Dibenzoyl-L-tartaricacid

  • Catalog NO.:A5323
  • CAS No. : 2743-38-6
  • Molecular Formula:C18H14O8
  • Molecular Weight: 358.30
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Product Details

CAS Number 2743-38-6 Appearance
Catalog Number A5323 MDL Number MFCD00003074
Molecular Formula C18H14O8 Molecular Weight 358.30
Boiling Point Melting Point 148-153°C
Flash Point Density
Synonyms (2R,3R)-2,3-bis(benzoyloxy)succinic acid;(-)-Dibenzoyl-L-tartaric acid
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H319 Class
Precautionary Statements P264; P280; P305+P351+P338; P337+P313 Packing Group

Description

FIPI is a potent and selective phospholipase D inhibitor. FIPI attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. FIPI rapidly blocks in vivo PA production with subnanomolar potency. We were surprised to find that several biological processes blocked by 1-butanol are not affected by FIPI, suggesting the need for re-evaluation of proposed FIPI does inhibit PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis, indicating potential utility for it as a therapeutic for autoimmunity and cancer metastasis.

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Dibenzoyl-L-tartaricacid
(2R,3R)-2,3-bis(benzoyloxy)succinic acid;(-)-Dibenzoyl-L-tartaric acid