P-methylcinnamaldehyde

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For R&D use only.

Catalog NO.：A869899
CAS No. : 56578-35-9
Molecular Formula：C₁₀H₁₀O
Molecular Weight： 146.19

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Product Details

CAS Number	56578-35-9	Appearance
Catalog Number	A869899	MDL Number	MFCD08460295
Molecular Formula	C₁₀H₁₀O	Molecular Weight	146.19
Boiling Point	267 oC	Melting Point	40-42 oC
Flash Point	94 oC	Density	1.015
Synonyms	(E)-3-(4-Methylphenyl)acrolein; (E)-4-Methylcinnamaldehyde; (E)-p-Methylcinnamaldehyde; trans-4-Methylcinnamaldehyde; trans-p-Methylcinnamaldehyde;(E)-3-(p-Tolyl)acrylaldehyde
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302-H315-H317-H319	Class
Precautionary Statements	P280-P305+P351+P338	Packing Group

Description

Romidepsin, also known as FK228; is a bicyclic depsipeptide antibiotic isolated from the bacterium Chromobacterium violaceum with antineoplastic activity. After intracellular activation, romidepsin binds to and inhibits histone deacetylase (HDAC), resulting in alterations in gene expression and the induction of cell differentiation, cell cycle arrest, and apoptosis. This agent also inhibits hypoxia-induced angiogenesis and depletes several heat shock protein 90 (Hsp90)-dependent oncoproteins.

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P401	Store …
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H200	Explosives (Unstable Explosive)
H201	Explosives （Div 1.1)
H202	Explosives (Div 1.2)
H203	Explosives (Div 1.3)
H204	Explosives (Div 1.4)
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H300	Acute toxicity,oral (Category 1, 2)
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H318	Serious eye damage/eye irritation (Category 1)
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H330	Acute toxicity,inhalation (Category 1, 2)
H331	Acute toxicity,inhalation (Category 3)
H332	Acute toxicity,inhalation (Category 4)
H333	Acute toxicity,inhalation (Category 5)
H334	Sensitisation, respiratory (Category 1)
H335	Specific target organ toxicity, single exposure; Respiratory tract irritation (Category 3)
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H340	Germ cell mutagenicity (Category 1A, 1B)
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H371	Specific target organ toxicity, single exposure (Category 2)
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H400	Hazardous to the aquatic environment, acute hazard (Category 1)
H401	Hazardous to the aquatic environment, acute hazard (Category 2)
H402	Hazardous to the aquatic environment, acute hazard (Category 3)
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