Pimasertib

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For R&D use only.

Catalog NO.：A857420
CAS No. : 1236699-92-5
Molecular Formula：C₁₅H₁₅FIn₃O₃
Molecular Weight： 431.20

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Quality Control&SDS

SDS COA NMR

Product Details

CAS Number	1236699-92-5	Appearance	Light yellow powder
Catalog Number	A857420	MDL Number	MFCD16660676
Molecular Formula	C₁₅H₁₅FIn₃O₃	Molecular Weight	431.20
Boiling Point		Melting Point
Flash Point		Density
Synonyms	AS-703026;N-[(2S)-2,3-Dihydroxypropyl]-3-[(2-fluoro-4-iodophenyl)amino]-4-pyridinecarboxamide;AS-703026
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302-H315-H319-H335	Class
Precautionary Statements	P261-P305+P351+P338	Packing Group

Description

Pimasertib, also known as AS703026, SAR245509, MSC1936369B, is a n orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity. MEK inhibitor AS703026 selectively binds to and inhibits the activity of MEK1/2, preventing the activation of MEK1/2-dependent effector proteins and transcription factors, which may result in the inhibition of growth factor-mediated cell signaling and tumor cell proliferation.

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H200	Explosives (Unstable Explosive)
H201	Explosives （Div 1.1)
H202	Explosives (Div 1.2)
H203	Explosives (Div 1.3)
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H318	Serious eye damage/eye irritation (Category 1)
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H330	Acute toxicity,inhalation (Category 1, 2)
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H332	Acute toxicity,inhalation (Category 4)
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H400	Hazardous to the aquatic environment, acute hazard (Category 1)
H401	Hazardous to the aquatic environment, acute hazard (Category 2)
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