2,4-Dimethyl-1H-pyrrole-3-carboxylicacidethylester

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For R&D use only.

Catalog NO.：A4721
CAS No. : 2199-51-1
Molecular Formula：C₉H₁₃NO₂
Molecular Weight： 167.21

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Quality Control&SDS

SDS COA NMR

Product Details

CAS Number	2199-51-1	Appearance	Red powder
Catalog Number	A4721	MDL Number	MFCD01365811
Molecular Formula	C₉H₁₃NO₂	Molecular Weight	167.21
Boiling Point	291°C at 760 mmHg	Melting Point
Flash Point		Density
Synonyms	ethyl 2,4-dimethyl-1H-pyrrole-3-carboxylate
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302-H315-H319-H335	Class
Precautionary Statements	P261-P305+P351+P338	Packing Group

Description

ABT-737 is an orally available inhibitor of the nuclear enzymes poly(ADP-ribose) polymerase (PARP) 1 and 2, with potential antineoplastic activity. Upon administration, ABT-767 selectively binds to PARP 1 and 2, thereby preventing repair of damaged DNA via the base excision repair (BER) pathway. This agent enhances the accumulation of DNA strand breaks and promotes genomic instability eventually leading to apoptosis. ABT-767 may enhance the cytotoxicity of DNA-damaging agents and reverse tumor cell chemo- and radioresistance.

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P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
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P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
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P370 + P378	In case of fire: Use … for extinction.
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P401	Store …
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P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
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H200	Explosives (Unstable Explosive)
H201	Explosives （Div 1.1)
H202	Explosives (Div 1.2)
H203	Explosives (Div 1.3)
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H318	Serious eye damage/eye irritation (Category 1)
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H330	Acute toxicity,inhalation (Category 1, 2)
H331	Acute toxicity,inhalation (Category 3)
H332	Acute toxicity,inhalation (Category 4)
H333	Acute toxicity,inhalation (Category 5)
H334	Sensitisation, respiratory (Category 1)
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H400	Hazardous to the aquatic environment, acute hazard (Category 1)
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