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  • Catalog NO.:A888561
  • CAS No. : 131211-27-3
  • Molecular Formula:C20H31P
  • Molecular Weight: 302.43
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Product Details

CAS Number 131211-27-3 Appearance
Catalog Number A888561 MDL Number MFCD06658117
Molecular Formula C20H31P Molecular Weight 302.43
Boiling Point Melting Point
Flash Point Density
Synonyms Di(adamantan-1-yl)phosphine
Storage Condition Store in a tightly closed container,in a cool and dry place


GHS Pictogram
Signal Word Danger UN Number 2811
Hazard Statements H301+H311+H331-H315-H319-H335 Class 6.1
Precautionary Statements P261-P280-P305+P351+P338-P311 Packing Group


BAY 87-2243 is a highly potent and selective inhibitor of hypoxia-induced gene activation, which has antitumor activities by inhibition of mitochondrial complex I. BAY 87-2243 mproves local tumor control after fractionated irradiation in a schedule-dependent manner in head and neck human xenografts. BAY-87-2243 markedly decreased nuclear HIF-1α expression and pimonidazole hypoxic fraction already after 3 days of drug treatment. BAY-87-2243 prior to RT significantly reduced TCD50 from 123 to 100 Gy (p=0.037). Additional BAY-87-2243 application during RT did not decrease TCD50.

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