For R&D use only.

1,3,5-Tris(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene

  • Catalog NO.:A874326
  • CAS No. : 365564-05-2
  • Molecular Formula:C24H39O6B3
  • Molecular Weight: 456.00
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Quality Control&SDS
SDS COA NMR

Product Details

CAS Number 365564-05-2 Appearance Off-white powder
Catalog Number A874326 MDL Number MFCD17167305
Molecular Formula C24H39O6B3 Molecular Weight 456.00
Boiling Point 555.6±45.0℃ at 760 mmHg Melting Point
Flash Point Density
Synonyms 1,3,5-Benzenetriboronic Acid Tris(pinacol) Ester
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302-H315-H319-H335 Class
Precautionary Statements P261-P305+P351+P338 Packing Group

Description

BAY 87-2243 is a highly potent and selective inhibitor of hypoxia-induced gene activation, which has antitumor activities by inhibition of mitochondrial complex I. BAY 87-2243 mproves local tumor control after fractionated irradiation in a schedule-dependent manner in head and neck human xenografts. BAY-87-2243 markedly decreased nuclear HIF-1α expression and pimonidazole hypoxic fraction already after 3 days of drug treatment. BAY-87-2243 prior to RT significantly reduced TCD50 from 123 to 100 Gy (p=0.037). Additional BAY-87-2243 application during RT did not decrease TCD50.

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1,3,5-Tris(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene
1,3,5-Benzenetriboronic Acid Tris(pinacol) Ester